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Duquesne Family Office 13F Portfolio ยท Stanley Druckenmiller

Portfolio Manager
Stanley Druckenmiller
Performance
+16.79% (2026 Q2)
AUM (13F)
$5.21B
# of Holdings
86
Performance Rank
Allocation (Top 20)
72.38%
Latest filing
Q2 2026

2026 Q2 ยท 13F Analysis

19.9% of Duquesne Family Office Sits in One Stock

Published September 20, 2026 ยท Based on the SEC 13F filing for 2026 Q2

Key takeaways

  • Health care still leads, but an 11.7-point cut funds everything else.
  • Natera is a 19.9% single-stock bet with a 165.1% unrealized gain.
  • New money favors semis, megacap internet, airlines and manufactured housing.
  • Bitcoin miners debut as a fresh 3.6% digital-infrastructure sleeve.
  • Broadcast media replaces streaming as the entertainment expression.

The thesis in one look

Duquesne Family Office used the second quarter to shrink its dominant bet without abandoning it. Health care's share of the 13F book fell from 45.34% to 33.65%, and nearly every dollar of that 11.7-point cut came back out as technology, consumer cyclicals, industrials and media, plus an entirely new digital-asset sleeve. This was a breadth quarter: 19 names entered the top 50, and the top 10 now account for 52.4% of reported assets.

The anchor is still Natera. At 19.86% of the book, worth $864.9M, it carries a +165.1% gain against Duquesne's average cost, and the fund added another 4.0% to the share count rather than scaling out. That is not a manager losing faith in diagnostics โ€” it is a manager treating a huge winner as collateral for the next set of ideas.

Strip Natera out and health care is closer to 13.8% of the book, spread across a long tail of clinical-stage names. Meanwhile the newly funded positions read as a macro statement: rate-sensitive cyclicals, AI hardware plumbing, broadcast assets and crypto-mining infrastructure. The fund returned 16.79% in the quarter, and its three-year annualized figure sits at 42.33%, so it is recycling profits from a position of strength.

Portfolio concentration
NTRA โ€” 21.6% ($864.92M)TSM โ€” 7.0% ($281.61M)STM โ€” 5.8% ($232.38M)INSM โ€” 3.8% ($151.90M)YPF โ€” 3.6% ($142.73M)AMZN โ€” 3.2% ($129.09M)TBBB โ€” 3.0% ($120.92M)GOOGL โ€” 3.0% ($120.18M)EWZ โ€” 3.0% ($118.55M)STX โ€” 2.9% ($117.73M)Other โ€” 43.1% ($1.73B)
57%in top 10
  • NTRA21.6%
  • TSM7.0%
  • STM5.8%
  • INSM3.8%
  • YPF3.6%
  • AMZN3.2%
  • TBBB3.0%
  • GOOGL3.0%
  • EWZ3.0%
  • STX2.9%
  • Other43.1%

Performance History

Performance Metric3-Year Annualized3-Year Cumulative5-Year Annualized5-Year Cumulative
Top 20 Holdings Weighted+42.33%+188.35%+24.79%+202.65%
Top 20 Holdings Unweighted+35.80%+150.42%+19.88%+147.62%

Fund Performance vs S&P 500

Exposure

Sector allocation

Current sector weights across the reported book, with the shift since last quarter.

Health Care33.6%โˆ’11.7%
Technology27.0%+5.6%
Consumer Discretionary14.6%+7.2%
Industrials7.5%+5.8%
Energy4.3%โˆ’4.0%
Unclassified3.7%โˆ’1.7%
Finance3.6%+3.6%
Consumer Staples3.0%โˆ’1.5%
Basic Materials2.1%โˆ’0.2%
Telecommunications0.6%โˆ’3.0%

Portfolio

Portfolio allocation

The fund's largest reported positions.

Top Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
NTRA
Natera Inc
19.86%3.19M$864.9M
+4.01%(+122.70K)
2025-Q2: 3.09M shares2025-Q3: 3.21M shares2025-Q4: 2.51M shares2026-Q1: 3.06M shares2026-Q2: 3.19M shares
$116.90(+165.11%)
2026-06-30
TSM
Taiwan Semiconductor Manufac
6.47%589.7K$281.6M
+19.06%(+94.40K)
2025-Q2: 765.1K shares2025-Q3: 765.1K shares2025-Q4: 543.1K shares2026-Q1: 495.3K shares2026-Q2: 589.7K shares
$213.12(+100.30%)
2026-06-30
STM
Stmicroelectronics N V
5.34%3.10M$232.4M
+18.75%(+490.00K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 773.6K shares2026-Q1: 2.61M shares2026-Q2: 3.10M shares
$33.07(+68.70%)
2026-06-30
INSM
Insmed Inc
3.49%1.42M$151.9M
+23.45%(+270.60K)
2025-Q2: 2.25M shares2025-Q3: 2.42M shares2025-Q4: 1.48M shares2026-Q1: 1.15M shares2026-Q2: 1.42M shares
$90.81(+36.27%)
2026-06-30
YPF
Ypf Sociedad Anonima
3.28%3.14M$142.7M
-3.00%(-97.06K)
2025-Q2: 704.0K shares2025-Q3: 114.7K shares2025-Q4: 607.0K shares2026-Q1: 3.24M shares2026-Q2: 3.14M shares
$39.15(+27.84%)
2026-06-30
AMZN
Amazon Com Inc
2.96%541.6K$129.1M
+1082.53%(+495.80K)
2025-Q2: 0 shares2025-Q3: 437.1K shares2025-Q4: 737.9K shares2026-Q1: 45.8K shares2026-Q2: 541.6K shares
$218.97(+19.89%)
2026-06-30
TBBB
Bbb Foods Inc
2.78%2.90M$120.9M
-6.67%(-207.47K)
2025-Q2: 360.6K shares2025-Q3: 1.18M shares2025-Q4: 2.68M shares2026-Q1: 3.11M shares2026-Q2: 2.90M shares
$29.68(+63.25%)
2026-06-30
GOOGL
Alphabet Inc
2.76%336.3K$120.2Mnew2025-Q2: 0 shares2025-Q3: 102.2K shares2025-Q4: 385.0K shares2026-Q1: 0 shares2026-Q2: 336.3K shares
$238.31(+44.65%)
2026-06-30
EWZ
Ishares Inc
2.72%3.44M$118.5M
+0.00%(+0)
2025-Q2: 738.8K shares2025-Q3: 0 shares2025-Q4: 3.55M shares2026-Q1: 3.44M shares2026-Q2: 3.44M shares
$30.56(+11.15%)
2026-06-30
STX
Seagate Technology Hldngs Pl
2.7%122.0K$117.7M
+140.63%(+71.30K)
2025-Q2: 197.5K shares2025-Q3: 85.9K shares2025-Q4: 0 shares2026-Q1: 50.7K shares2026-Q2: 122.0K shares
$419.29(+138.32%)
2026-06-30

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
19
GOOGLAlphabet Inc2.8%
FOXAFox Corp2.6%
CDWCdw Corp2.4%
BTDRBitdeer Technologies Group1.5%
+15 opened
Added to
15
AMZNAmazon Com Inc+1082.5%
UALUnited Airls Hldgs Inc+202.8%
STXSeagate Technology Hldngs Pl+140.6%
TSMTaiwan Semiconductor Manufac+19.1%
+11 more
Trimmed
7
ROKURoku Inc-75.5%
WWDWoodward Inc-68.2%
TEVATeva Pharmaceutical Inds Ltd-73.7%
TBBBBbb Foods Inc-6.7%
+3 more

Where conviction is rising: compute plumbing, megacap internet, owned media

The new dollars cluster into a handful of themes, and they are mostly second-derivative trades rather than the obvious headline names.

  • Semis and the hardware underneath AI: Taiwan Semiconductor rose 19.1% to $281.6M and STMicroelectronics 18.8% to $232.4M, while AMD, Rambus and Qnity Electronics are all new to the book. Seagate's 140.6% increase to $117.7M is the tell โ€” this is storage and memory, not GPU bravado.
  • Megacap internet: Amazon's share count went up 1082.5% to $129.1M, and Alphabet is a brand-new $120.2M position. Both show only modest gains versus average cost, so Duquesne is paying up rather than harvesting.
  • Owned media: Fox's two share classes arrived together, FOXA at $115.0M and FOX at $29.6M. Combined, roughly $144.6M is a bigger commitment than almost anything else in the portfolio.
  • Transport and shelter: United Airlines more than tripled to $108.1M, Delta is new at $56.5M, and D.R. Horton, Cavco and Champion Homes all debuted. That is a rate-cut expression more than a stock-picking one.

The common thread is that none of these require the market's most crowded trade to keep working.

Conviction

The big buys

The biggest dollar adds this quarter โ€” where conviction is rising.

PositionChangePortfolio weightValue
GOOGLAlphabet IncNew+$120.2M2.8%$120.2M
AMZNAmazon Com IncAdded 1082.5%+$118.2M3.0%$129.1M
FOXAFox CorpNew+$115.0M2.6%$115.0M
CDWCdw CorpNew+$104.6M2.4%$104.6M
UALUnited Airls Hldgs IncAdded 202.8%+$72.4M2.5%$108.1M
STXSeagate Technology Hldngs PlAdded 140.6%+$68.8M2.7%$117.7M
BTDRBitdeer Technologies GroupNew+$64.7M1.5%$64.7M
DALDelta Air Lines IncNew+$56.5M1.3%$56.5M

Dollar changes estimated at current prices (shares added ร— current price); top-50 current positions only.

The funding trades: Roku, Woodward and Teva pay the bill

Almost every large trim sits on a substantial unrealized gain, which is what makes this look like funding rather than fear.

  • Roku: shares cut 75.5%, releasing $78.2M, with a +91.7% gain versus average cost. The proceeds went straight into the two Fox classes โ€” a swap out of streaming hardware economics into broadcast.
  • Woodward: down 68.2%, $61.3M out, after a +153.7% run. This is an aerospace and industrial-controls business, not an energy company, despite its sector label.
  • Teva Pharmaceutical: 73.7% lower, $59.4M released, at a +93.7% gain. That single cut explains a meaningful slice of health care's weight loss.
  • Sandisk: trimmed 8.5%, but the remaining stake still carries a +2138.2% gain versus cost. When a winner is up that much, a trim is housekeeping, not a verdict.
  • BBB Foods fell 6.7% and YPF 3.0% โ€” small shaves that top up the larger bets.

Note what is missing: no mega-cap tech liquidation, no dumping of the semiconductor adds. Duquesne is selling winners it considers fully valued to buy winners it thinks are earlier.

The rotation under the hood: the labels lie, but the drift is real

The sector chart says consumer discretionary nearly doubled, from 7.36% to 14.56%, and that industrials went from 1.69% to 7.45%. Read carefully, because the NASDAQ labels are doing sloppy work here. Fox and Fox A are broadcasters โ€” communication services businesses, not industrial ones โ€” so most of the "industrials" jump is really a media bet. Roku's old "telecommunications" tag was never telecom either.

On the technology side, the weight climbed from 21.42% to 27.03%, and that understates things. Entegris is a semiconductor materials supplier filed under plastics, and Qnity is an electronics spin-off; both belong in the AI supply chain. The genuine compute-infrastructure exposure is meaningfully larger than the label suggests, and it is concentrated in memory, storage and analog rather than the GPU names everyone owns.

The real collapse is energy, 8.33% to 4.28%. Part of that is an artifact: Woodward's cut explains a lot of it, and Woodward was never an oil company. The other honest shift is finance, from nothing to 3.61%, which is entirely four crypto-linked miners. Net-net, a health-care book with a tech sleeve became a diversified compute-and-cyclical book with one huge medical anchor.

2026 Q12026 Q2Health care & biotechHealth care & biotech โ€” 2026 Q1: 45.34%45.34%Health care & biotech โ€” 2026 Q2: 33.65%33.65% โˆ’11.7ptTech, semis & hardwareTech, semis & hardware โ€” 2026 Q1: 21.42%21.42%Tech, semis & hardware โ€” 2026 Q2: 27.03%27.03% +5.6ptConsumer, travel & housingConsumer, travel & housing โ€” 2026 Q1: 7.36%7.36%Consumer, travel & housing โ€” 2026 Q2: 14.56%14.56% +7.2ptIndustrials & mediaIndustrials & media โ€” 2026 Q1: 1.69%1.69%Industrials & media โ€” 2026 Q2: 7.45%7.45% +5.8ptEnergyEnergy โ€” 2026 Q1: 8.33%8.33%Energy โ€” 2026 Q2: 4.28%4.28% โˆ’4.0ptDigital-asset minersDigital-asset miners โ€” 2026 Q1: 0%0%Digital-asset miners โ€” 2026 Q2: 3.61%3.61% +3.6pt
Portfolio weight by theme, 2026 Q1 (estimated at current prices) vs 2026 Q2.

What this sets up going into the second half

The through-line is a portfolio positioned for two things at once: a broadening AI capital-expenditure cycle that pays memory, storage, analog and IT distribution, and a rate-relief cycle that revives airlines and homebuilders. Both are second-derivative expressions, which is consistent with a manager who would rather own the picks and shovels than the headline.

The speculative sleeve is the interesting tell. Bitdeer at $64.7M sits 23.1% below average cost, Hut 8, Riot and Hyperliquid Strategies are all new, and together the digital-asset complex is roughly 3.6% of the book. That looks like an option on power and compute scarcity, sized so a wipeout would not matter.

The risk is concentration. Natera at 19.86% means one clinical or reimbursement headline can move the whole book, and health care at 33.65% still exceeds technology. If biotech risk appetite sours, both the anchor and the funding engine for these new positions weaken at the same time. The rotation is real, but it is being financed by a single name's gains โ€” and that is the position to watch next quarter.

Frequently asked questions

What did Duquesne Family Office buy in 2026-Q2?+

It added 19 new positions to its top 50, including Alphabet at $120.2M, both Fox share classes, CDW, Delta Air Lines, AMD, Palo Alto Networks, D.R. Horton and four crypto-linked miners. It also expanded existing stakes in Amazon, United Airlines, Seagate and Taiwan Semiconductor.

What is Duquesne Family Office's biggest holding?+

Natera Inc, at 19.86% of the reported book and roughly $864.9M in value. The fund added another 4.0% to the share count during the quarter, and the position sits on a +165.1% gain versus average cost.

How much of Duquesne's portfolio is in health care?+

Health care was 33.65% of the book at 2026-Q2 quarter-end, down from an estimated 45.34% the prior quarter. Most of that reduction came from the Teva Pharmaceutical cut rather than from Natera, which was added to.

Did Duquesne Family Office sell Roku?+

It cut the Roku position by 75.5%, releasing about $78.2M, at a +91.7% gain versus average cost. The proceeds went into Fox's two share classes, a fairly direct swap out of streaming into broadcast.

What is Duquesne's bitcoin and crypto exposure?+

Four new crypto-linked positions: Bitdeer Technologies, Hut 8, Riot Platforms and Hyperliquid Strategies. Together they make up roughly 3.6% of the reported book, mostly bought below or near current prices.

How concentrated is Duquesne Family Office's portfolio?+

The top 10 positions account for 52.4% of reported assets, and Natera alone is 19.86%. The 50 disclosed positions cover the large majority of the $5.21B 13F book.

Source filings

Holdings on this page are parsed from Duquesne Family Office LLCโ€™s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1536411). View Duquesne Family Office LLCโ€™s 13F filings on SEC

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