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Opaleye Management INC

Portfolio Manager
Opaleye Management INC
Performance
+0.34% (2026 Q1)
AUM (13F)
$759.22M
# of Holdings
54
Performance Rank
Allocation (Top 20)
82.23%

Opaleye Management INC Holdings Map

Top 50 Opaleye Management INC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
HROW
HARROW INC
13.15%2.83M$99.9M
-27.47%(-1.07M)
2025-Q1: 3.96M shares2025-Q2: 3.90M shares2025-Q3: 3.90M shares2025-Q4: 3.90M shares2026-Q1: 2.83M shares
$6.49(+558.45%)
2026-03-31
LQDA
LIQUIDIA CORPORATION
11.7%2.54M$88.8M
+4.52%(+110.00K)
2025-Q1: 2.26M shares2025-Q2: 2.48M shares2025-Q3: 2.62M shares2025-Q4: 2.44M shares2026-Q1: 2.54M shares
$12.49(+532.16%)
2026-03-31
ETON
ETON PHARMACEUTICALS INC
9.3%2.86M$70.6M
+0.00%(+0)
2025-Q1: 2.85M shares2025-Q2: 2.86M shares2025-Q3: 2.86M shares2025-Q4: 2.86M shares2026-Q1: 2.86M shares
$5.78(+548.97%)
2026-03-31
SLGL
SOL-GEL TECHNOLOGIES LTD
5.22%500.0K$39.6M
+10.20%(+46.26K)
2025-Q1: 0 shares2025-Q2: 0 shares2025-Q3: 204.8K shares2025-Q4: 453.7K shares2026-Q1: 500.0K shares
$30.85(+139.94%)
2026-03-31
RYTM
RHYTHM PHARMACEUTICALS INC
4.65%123.0K$35.3M
-62.73%(-207.00K)
2025-Q1: 490.0K shares2025-Q2: 475.0K shares2025-Q3: 461.7K shares2025-Q4: 330.0K shares2026-Q1: 123.0K shares
$11.39(+902.67%)
2026-03-31
APGE
APOGEE THERAPEUTICS INC
4.32%390.0K$32.8M
+0.45%(+1.74K)
2025-Q1: 0 shares2025-Q2: 0 shares2025-Q3: 363.3K shares2025-Q4: 388.3K shares2026-Q1: 390.0K shares
$42.78(+210.70%)
2026-03-31
IRON
DISC MEDICINE INC
3.55%421.0K$26.9M
+110.50%(+221.00K)
2025-Q1: 85.0K shares2025-Q2: 186.4K shares2025-Q3: 193.8K shares2025-Q4: 200.0K shares2026-Q1: 421.0K shares
$63.84(+19.46%)
2026-03-31
URGN
UROGEN PHARMA LTD
3.39%1.43M$25.7M
+432.74%(+1.16M)
2025-Q1: 0 shares2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 268.4K shares2026-Q1: 1.43M shares
$19.26(+97.40%)
2026-03-31
CBIO
CRESCENT BIOPHARMA INC.
3.18%1.31M$24.1M
+11.40%(+134.31K)
2025-Q1: 0 shares2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 1.18M shares2026-Q1: 1.31M shares
$12.21(+40.01%)
2026-03-31
STOK
STOKE THERAPEUTICS INC
3%700.0K$22.8M
+0.72%(+5.00K)
2025-Q1: 300.0K shares2025-Q2: 562.1K shares2025-Q3: 682.0K shares2025-Q4: 695.0K shares2026-Q1: 700.0K shares
$11.09(+194.84%)
2026-03-31

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