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Arch Venture Management 13F Portfolio

Portfolio Manager
Arch Venture Management LLC
Performance
+15.67% (2026 Q2)
AUM (13F)
$1.10B
# of Holdings
12
Performance Rank
Allocation (Top 20)
68.66%
Latest filing
Q2 2026

Arch Venture Management LLC Holdings Map

Top 9 Arch Venture Management LLC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
BEAM
BEAM THERAPEUTICS INC
14.16%4.54M$155.8M
+0.00%(+0)
2025-Q2: 4.54M shares2025-Q3: 4.54M shares2025-Q4: 4.54M shares2026-Q1: 4.54M shares2026-Q2: 4.54M shares
$28.24(-5.26%)
2026-06-30
RAPP
RAPPORT THERAPEUTICS INC
14.12%3.73M$155.4M
+0.00%(+0)
2025-Q2: 3.73M shares2025-Q3: 3.73M shares2025-Q4: 3.73M shares2026-Q1: 3.73M shares2026-Q2: 3.73M shares
$23.26(+103.87%)
2026-06-30
ERAS
ERASCA INC
11.81%7.09M$129.9M
+0.00%(+0)
2025-Q2: 11.06M shares2025-Q3: 11.06M shares2025-Q4: 11.06M shares2026-Q1: 7.09M shares2026-Q2: 7.09M shares
$18.40(-0.11%)
2026-06-30
VIR
VIR BIOTECHNOLOGY INC
11.76%12.69M$129.4M
-1.72%(-222.50K)
2025-Q2: 12.92M shares2025-Q3: 12.92M shares2025-Q4: 12.92M shares2026-Q1: 12.92M shares2026-Q2: 12.69M shares
$5.87(+57.41%)
2026-06-30
MAZE
MAZE THERAPEUTICS INC
11.18%4.12M$123.0M
+0.00%(+0)
2025-Q2: 4.12M shares2025-Q3: 4.12M shares2025-Q4: 4.12M shares2026-Q1: 4.12M shares2026-Q2: 4.12M shares
$11.01(+146.87%)
2026-06-30
LYEL
LYELL IMMUNOPHARMA INC
4.14%3.25M$45.5M
+0.00%(+0)
2025-Q2: 1.82M shares2025-Q3: 2.76M shares2025-Q4: 2.76M shares2026-Q1: 3.25M shares2026-Q2: 3.25M shares
$12.96(+7.67%)
2026-06-30
TXG
10X GENOMICS INC
0.76%217.8K$8.4M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 737.5K shares2026-Q1: 217.8K shares2026-Q2: 217.8K shares
$14.00(+300.64%)
2026-06-30
BOLD
BOUNDLESS BIO INC
0.61%2.69M$6.7Mnew2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 0 shares2026-Q2: 2.69M shares
$1.79(+60.95%)
2026-06-30
GOSS
GOSSAMER BIO INC
0.12%8.06M$1.3M
+0.00%(+0)
2025-Q2: 8.06M shares2025-Q3: 8.06M shares2025-Q4: 8.06M shares2026-Q1: 8.06M shares2026-Q2: 8.06M shares
$1.02(-84.83%)
2026-06-30

About Arch Venture Management LLC’s portfolio

Arch Venture Management LLC reports $1.10B in US-listed equity holdings across 12 positions in its most recent 13F filing. Its largest disclosed positions are BEAM (14.2%), RAPP (14.1%) and ERAS (11.8%). The top 20 holdings account for 68.66% of reported assets. Its disclosed equity book has returned +61.58% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
BEAM — 20.6% ($155.77M)RAPP — 20.6% ($155.38M)ERAS — 17.2% ($129.92M)VIR — 17.1% ($129.35M)MAZE — 16.3% ($122.98M)LYEL — 6.0% ($45.53M)TXG — 1.1% ($8.35M)BOLD — 0.9% ($6.74M)GOSS — 0.2% ($1.33M)
100%in top 9
  • BEAM20.6%
  • RAPP20.6%
  • ERAS17.2%
  • VIR17.1%
  • MAZE16.3%
  • LYEL6.0%
  • TXG1.1%
  • BOLD0.9%
  • GOSS0.2%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
1
BOLDBOUNDLESS BIO INC0.6%
Trimmed
1
VIRVIR BIOTECHNOLOGY INC-1.7%

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Source filings

Holdings on this page are parsed from Arch Venture Management LLC’s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1274403). View Arch Venture Management LLC’s 13F filings on SEC

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