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Avidity Partners Management 13F Portfolio

Portfolio Manager
Avidity Partners Management LP
Performance
+17.94% (2026 Q2)
AUM (13F)
$624.44M
# of Holdings
45
Performance Rank
Allocation (Top 20)
90.74%
Latest filing
Q2 2026

Avidity Partners Management LP Holdings Map

Top 39 Avidity Partners Management LP Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
DNTH
DIANTHUS THERAPEUTICS INC
32.85%2.10M$205.1M
+0.00%(+0)
2025-Q2: 1.74M shares2025-Q3: 3.20M shares2025-Q4: 2.10M shares2026-Q1: 2.10M shares2026-Q2: 2.10M shares
$22.85(+407.39%)
2026-06-30
CGON
CG ONCOLOGY INC
15.92%1.40M$99.4M
+8.53%(+110.00K)
2025-Q2: 1.50M shares2025-Q3: 1.60M shares2025-Q4: 1.47M shares2026-Q1: 1.29M shares2026-Q2: 1.40M shares
$38.71(+95.29%)
2026-06-30
ORKA
ORUKA THERAPEUTICS INC
11.59%760.4K$72.4M
+0.00%(+0)
2025-Q2: 352.1K shares2025-Q3: 660.4K shares2025-Q4: 660.4K shares2026-Q1: 760.4K shares2026-Q2: 760.4K shares
$27.70(+306.03%)
2026-06-30
JBIO
JADE BIOSCIENCES INC
6.05%1.70M$37.8M
+21.42%(+300.00K)
2025-Q2: 1.13M shares2025-Q3: 1.13M shares2025-Q4: 1.40M shares2026-Q1: 1.40M shares2026-Q2: 1.70M shares
$37.72(-34.49%)
2026-06-30
ELVN
ENLIVEN THERAPEUTICS INC
4.47%550.0K$27.9M
+37.50%(+150.00K)
2025-Q2: 11.3K shares2025-Q3: 140.3K shares2025-Q4: 140.3K shares2026-Q1: 400.0K shares2026-Q2: 550.0K shares
$29.99(+96.15%)
2026-06-30
CATX
PERSPECTIVE THERAPEUTICS INC
3.44%6.30M$21.5M
+4.13%(+250.00K)
2025-Q2: 1.86M shares2025-Q3: 2.99M shares2025-Q4: 3.21M shares2026-Q1: 6.05M shares2026-Q2: 6.30M shares
$5.68(-43.66%)
2026-06-30
AKTS
AKTIS ONCOLOGY INC
2.5%484.2K$15.6M
+3.34%(+15.63K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 468.6K shares2026-Q2: 484.2K shares
$18.10(+37.74%)
2026-06-30
PVLA
PALVELLA THERAPEUTICS INC NE
1.71%70.0K$10.7M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 19.3K shares2026-Q1: 70.0K shares2026-Q2: 70.0K shares
$106.12(+47.13%)
2026-06-30
RGEN
REPLIGEN CORP
1.7%77.8K$10.6M
+0.00%(+0)
2025-Q2: 106.5K shares2025-Q3: 23.3K shares2025-Q4: 50.3K shares2026-Q1: 77.8K shares2026-Q2: 77.8K shares
$140.01(+19.15%)
2026-06-30
SENS
SENSEONICS HLDGS INC
1.46%1.60M$9.1Mnew2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 0 shares2026-Q2: 1.60M shares
$5.93(+31.70%)
2026-06-30

About Avidity Partners Management LPโ€™s portfolio

Avidity Partners Management LP reports $624.44M in US-listed equity holdings across 45 positions in its most recent 13F filing. Its largest disclosed positions are DNTH (32.9%), CGON (15.9%) and ORKA (11.6%). The top 20 holdings account for 90.74% of reported assets. Its disclosed equity book has returned +97.35% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
DNTH โ€” 34.4% ($205.12M)CGON โ€” 16.7% ($99.40M)ORKA โ€” 12.1% ($72.37M)JBIO โ€” 6.3% ($37.79M)ELVN โ€” 4.7% ($27.91M)CATX โ€” 3.6% ($21.48M)AKTS โ€” 2.6% ($15.61M)PVLA โ€” 1.8% ($10.70M)RGEN โ€” 1.8% ($10.62M)SENS โ€” 1.5% ($9.09M)Other โ€” 14.4% ($85.60M)
86%in top 10
  • DNTH34.4%
  • CGON16.7%
  • ORKA12.1%
  • JBIO6.3%
  • ELVN4.7%
  • CATX3.6%
  • AKTS2.6%
  • PVLA1.8%
  • RGEN1.8%
  • SENS1.5%
  • Other14.4%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
9
SENSSENSEONICS HLDGS INC1.5%
NVCTNUVECTIS PHARMA INC0.6%
PODDINSULET CORP0.6%
CRLCHARLES RIV LABS INTL INC0.4%
+5 opened
Added to
11
CGONCG ONCOLOGY INC+8.5%
ELVNENLIVEN THERAPEUTICS INC+37.5%
JBIOJADE BIOSCIENCES INC+21.4%
TEMTEMPUS AI INC+320.0%
+7 more
Trimmed
6
TEVATEVA PHARMACEUTICAL INDS LTD-55.6%
VIRVIR BIOTECHNOLOGY INC-45.3%
MDTMEDTRONIC PLC-30.0%
PTONPELOTON INTERACTIVE INC-50.0%
+2 more

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Source filings

Holdings on this page are parsed from Avidity Partners Management LPโ€™s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1791827). View Avidity Partners Management LPโ€™s 13F filings on SEC

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