Top 32 Commodore Capital LP Holdings
| Stock | Company | % Port. | Shares | Value | Activity | Ownership | Avg. Cost | Date |
|---|---|---|---|---|---|---|---|---|
| RLAY | RELAY THERAPEUTICS INC | 13.37% | 12.00M | $224.5M | -29.41%(-5.00M) | $3.36(+491.36%) | 2026-06-30 | |
| ELVN | ENLIVEN THERAPEUTICS INC | 9.9% | 3.27M | $166.2M | +0.00%(+0) | $18.84(+212.19%) | 2026-06-30 | |
| ALKS | ALKERMES PLC | 9.36% | 3.00M | $157.2M | -28.57%(-1.20M) | $28.21(+73.89%) | 2026-06-30 | |
| COGT | COGENT BIOSCIENCES INC | 7.03% | 3.05M | $118.0M | +5.61%(+161.99K) | $17.49(+116.83%) | 2026-06-30 | |
| AMLX | AMYLYX PHARMACEUTICALS INC | 6.04% | 5.65M | $101.5M | +0.00%(+0) | $10.79(+100.46%) | 2026-06-30 | |
| DFTX | DEFINIUM THERAPEUTICS INC | 5.6% | 2.00M | $94.1M | +0.00%(+0) | $16.14(+164.04%) | 2026-06-30 | |
| SYRE | SPYRE THERAPEUTICS INC | 4.48% | 846.8K | $75.2M | -55.72%(-1.07M) | $18.44(+462.10%) | 2026-06-30 | |
| ANRO | ALTO NEUROSCIENCE INC | 4.28% | 2.72M | $71.9M | +0.00%(+0) | $13.96(+130.22%) | 2026-06-30 | |
| TNGX | TANGO THERAPEUTICS INC | 4.19% | 2.25M | $70.3M | new | $10.61(+141.32%) | 2026-06-30 | |
| EYPT | EYEPOINT INC | 3.92% | 4.60M | $65.8M | +62.83%(+1.77M) | $14.61(+0.93%) | 2026-06-30 |
| Performance Metric | 3-Year Annualized | 3-Year Cumulative | 5-Year Annualized | 5-Year Cumulative |
|---|---|---|---|---|
| Top 20 Holdings Weighted | +39.72% | +172.73% | +16.63% | +115.84% |
| Top 20 Holdings Unweighted | +41.78% | +185.00% | +9.53% | +57.66% |
Commodore Capital LP reports $1.68B in US-listed equity holdings across 33 positions in its most recent 13F filing. Its largest disclosed positions are RLAY (13.4%), ELVN (9.9%) and ALKS (9.4%). The top 20 holdings account for 91.87% of reported assets. Its disclosed equity book has returned +172.73% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.
Portfolio changes
Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.
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Holdings on this page are parsed from Commodore Capital LPโs Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1831942). View Commodore Capital LPโs 13F filings on SEC