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Flagship Pioneering 13F Portfolio

Portfolio Manager
Flagship Pioneering LLC
Performance
+27.62% (2026 Q2)
AUM (13F)
$1.54B
# of Holdings
5
Performance Rank
Allocation (Top 20)
31.35%
Latest filing
Q2 2026

Flagship Pioneering LLC Holdings Map

Top 4 Flagship Pioneering LLC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
MRNA
MODERNA INC
21.07%4.63M$324.4M
+0.00%(+0)
2025-Q2: 4.63M shares2025-Q3: 4.63M shares2025-Q4: 4.63M shares2026-Q1: 4.63M shares2026-Q2: 4.63M shares
$15.27(+314.67%)
2026-06-30
SANA
SANA BIOTECHNOLOGY INC
5.67%25.00M$87.3M
+0.00%(+0)
2025-Q2: 25.00M shares2025-Q3: 25.00M shares2025-Q4: 25.00M shares2026-Q1: 25.00M shares2026-Q2: 25.00M shares
$33.47(-89.39%)
2026-06-30
FHTX
FOGHORN THERAPEUTICS INC
4.02%12.67M$61.8M
+0.00%(+0)
2025-Q2: 12.67M shares2025-Q3: 12.67M shares2025-Q4: 12.67M shares2026-Q1: 12.67M shares2026-Q2: 12.67M shares
$20.27(-69.12%)
2026-06-30
MCRB
SERES THERAPEUTICS INC
0.59%1.16M$9.1M
+0.00%(+0)
2025-Q2: 1.16M shares2025-Q3: 1.16M shares2025-Q4: 1.16M shares2026-Q1: 1.16M shares2026-Q2: 1.16M shares
$214.27(-97.88%)
2026-06-30

About Flagship Pioneering LLC’s portfolio

Flagship Pioneering LLC reports $1.54B in US-listed equity holdings across 5 positions in its most recent 13F filing. Its largest disclosed positions are MRNA (21.1%), SANA (5.7%) and FHTX (4.0%). The top 20 holdings account for 31.35% of reported assets. Its disclosed equity book has returned -45.54% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
MRNA — 67.2% ($324.39M)SANA — 18.1% ($87.26M)FHTX — 12.8% ($61.85M)MCRB — 1.9% ($9.12M)
100%in top 4
  • MRNA67.2%
  • SANA18.1%
  • FHTX12.8%
  • MCRB1.9%

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Source filings

Holdings on this page are parsed from Flagship Pioneering LLC’s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1400240). View Flagship Pioneering LLC’s 13F filings on SEC

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