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Foresite Capital Management IV 13F Portfolio

Portfolio Manager
Foresite Capital Management IV LLC
Performance
+20.46% (2026 Q2)
AUM (13F)
$290.15M
# of Holdings
6
Performance Rank
Allocation (Top 20)
99.99%
Latest filing
Q2 2026

Foresite Capital Management IV LLC Holdings Map

Top 6 Foresite Capital Management IV LLC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
PHVS
Pharvaris N.V.
56.95%4.78M$165.2M
+0.00%(+0)
2025-Q2: 4.41M shares2025-Q3: 4.78M shares2025-Q4: 4.78M shares2026-Q1: 4.78M shares2026-Q2: 4.78M shares
$24.90(+41.12%)
2026-06-30
CYTK
CYTOKINETICS INC
20.98%714.7K$60.9M
+42.00%(+211.40K)
2025-Q2: 0 shares2025-Q3: 458.3K shares2025-Q4: 458.3K shares2026-Q1: 503.3K shares2026-Q2: 714.7K shares
$54.20(+36.77%)
2026-06-30
EIKN
Eikon Therapeutics, Inc.
8.74%1.94M$25.4M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 1.94M shares2026-Q2: 1.94M shares
$10.58(+4.44%)
2026-06-30
RLAY
Relay Therapeutics, Inc.
8.06%1.25M$23.4M
+25.00%(+250.00K)
2025-Q2: 1.00M shares2025-Q3: 1.00M shares2025-Q4: 1.00M shares2026-Q1: 1.00M shares2026-Q2: 1.25M shares
$8.25(+140.84%)
2026-06-30
XENE
Xenon Pharmaceuticals Inc.
3.33%160.0K$9.7M
+0.00%(+0)
2025-Q2: 160.0K shares2025-Q3: 160.0K shares2025-Q4: 160.0K shares2026-Q1: 160.0K shares2026-Q2: 160.0K shares
$32.78(+90.21%)
2026-06-30
CRNX
Crinetics Pharmaceuticals, Inc.
1.93%150.0K$5.6Mnew2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 0 shares2026-Q2: 150.0K shares
$35.84(+136.30%)
2026-06-30

About Foresite Capital Management IV LLC’s portfolio

Foresite Capital Management IV LLC reports $290.15M in US-listed equity holdings across 6 positions in its most recent 13F filing. Its largest disclosed positions are PHVS (57.0%), CYTK (21.0%) and EIKN (8.7%). The top 20 holdings account for 99.99% of reported assets. Its disclosed equity book has returned +39.75% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
PHVS — 57.0% ($165.24M)CYTK — 21.0% ($60.88M)EIKN — 8.7% ($25.37M)RLAY — 8.1% ($23.39M)XENE — 3.3% ($9.66M)CRNX — 1.9% ($5.61M)
100%in top 6
  • PHVS57.0%
  • CYTK21.0%
  • EIKN8.7%
  • RLAY8.1%
  • XENE3.3%
  • CRNX1.9%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
1
CRNXCrinetics Pharmaceuticals, Inc.1.9%
Added to
2
CYTKCYTOKINETICS INC+42.0%
RLAYRelay Therapeutics, Inc.+25.0%

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Source filings

Holdings on this page are parsed from Foresite Capital Management IV LLC’s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1704132). View Foresite Capital Management IV LLC’s 13F filings on SEC

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