Top 38 Frazier Life Sciences Management L P Holdings
| Stock | Company | % Port. | Shares | Value | Activity | Ownership | Avg. Cost | Date |
|---|---|---|---|---|---|---|---|---|
| MIRM | MIRUM PHARMACEUTICALS INC | 19.58% | 7.68M | $899.1M | +0.00%(+0) | $30.66(+228.24%) | 2026-06-30 | |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 13.35% | 18.09M | $613.0M | +6.76%(+1.15M) | $14.82(+81.99%) | 2026-06-30 | |
| ERAS | ERASCA INC | 9.96% | 24.98M | $457.5M | +1.22%(+300.00K) | $2.99(+514.84%) | 2026-06-30 | |
| MBX | MBX BIOSCIENCES INC | 8% | 6.65M | $367.2M | +0.00%(+0) | $24.82(+176.21%) | 2026-06-30 | |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 5.64% | 9.87M | $258.9M | +0.00%(+0) | $19.28(+35.81%) | 2026-06-30 | |
| TRVI | TREVI THERAPEUTICS INC | 4.04% | 9.94M | $185.4M | -0.00%(-100) | $2.63(+602.46%) | 2026-06-30 | |
| KRYS | KRYSTAL BIOTECH INC | 3.9% | 481.3K | $178.9M | +0.00%(+0) | $69.22(+380.04%) | 2026-06-30 | |
| MAZE | MAZE THERAPEUTICS INC | 3.27% | 5.03M | $150.2M | +10.20%(+465.64K) | $12.79(+112.57%) | 2026-06-30 | |
| PHAT | PHATHOM PHARMACEUTICALS INC | 2.95% | 12.47M | $135.3M | +0.00%(+0) | $12.77(-25.77%) | 2026-06-30 | |
| PVLA | PALVELLA THERAPEUTICS INC NE | 2.94% | 882.4K | $134.8M | +0.00%(+0) | $33.13(+371.30%) | 2026-06-30 |
| Performance Metric | 3-Year Annualized | 3-Year Cumulative | 5-Year Annualized | 5-Year Cumulative | Since First Filing (17 quarters) |
|---|---|---|---|---|---|
| Top 20 Holdings Weighted | +39.86% | +173.56% | โ | โ | +161.96% |
| Top 20 Holdings Unweighted | +43.23% | +193.81% | โ | โ | +181.15% |
Frazier Life Sciences Management L P reports $4.59B in US-listed equity holdings across 41 positions in its most recent 13F filing. Its largest disclosed positions are MIRM (19.6%), NAMS (13.3%) and ERAS (10.0%). The top 20 holdings account for 88.81% of reported assets. Its disclosed equity book has returned +173.56% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.
Portfolio changes
Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.
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Holdings on this page are parsed from Frazier Life Sciences Management L Pโs Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1892134). View Frazier Life Sciences Management L Pโs 13F filings on SEC