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Frazier Life Sciences Management L P 13F Portfolio

Portfolio Manager
Frazier Life Sciences Management L P
Performance
+20.98% (2026 Q2)
AUM (13F)
$4.59B
# of Holdings
41
Performance Rank
Allocation (Top 20)
88.81%
Latest filing
Q2 2026

Frazier Life Sciences Management L P Holdings Map

Top 38 Frazier Life Sciences Management L P Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
MIRM
MIRUM PHARMACEUTICALS INC
19.58%7.68M$899.1M
+0.00%(+0)
2025-Q2: 6.80M shares2025-Q3: 6.80M shares2025-Q4: 6.80M shares2026-Q1: 7.68M shares2026-Q2: 7.68M shares
$30.66(+228.24%)
2026-06-30
NAMS
NEWAMSTERDAM PHARMA COMPANY
13.35%18.09M$613.0M
+6.76%(+1.15M)
2025-Q2: 16.61M shares2025-Q3: 16.70M shares2025-Q4: 16.94M shares2026-Q1: 16.94M shares2026-Q2: 18.09M shares
$14.82(+81.99%)
2026-06-30
ERAS
ERASCA INC
9.96%24.98M$457.5M
+1.22%(+300.00K)
2025-Q2: 22.73M shares2025-Q3: 22.73M shares2025-Q4: 22.73M shares2026-Q1: 24.68M shares2026-Q2: 24.98M shares
$2.99(+514.84%)
2026-06-30
MBX
MBX BIOSCIENCES INC
8%6.65M$367.2M
+0.00%(+0)
2025-Q2: 5.99M shares2025-Q3: 6.65M shares2025-Q4: 6.65M shares2026-Q1: 6.65M shares2026-Q2: 6.65M shares
$24.82(+176.21%)
2026-06-30
ARQT
ARCUTIS BIOTHERAPEUTICS INC
5.64%9.87M$258.9M
+0.00%(+0)
2025-Q2: 9.87M shares2025-Q3: 9.87M shares2025-Q4: 9.87M shares2026-Q1: 9.87M shares2026-Q2: 9.87M shares
$19.28(+35.81%)
2026-06-30
TRVI
TREVI THERAPEUTICS INC
4.04%9.94M$185.4M
-0.00%(-100)
2025-Q2: 10.26M shares2025-Q3: 10.26M shares2025-Q4: 10.26M shares2026-Q1: 9.94M shares2026-Q2: 9.94M shares
$2.63(+602.46%)
2026-06-30
KRYS
KRYSTAL BIOTECH INC
3.9%481.3K$178.9M
+0.00%(+0)
2025-Q2: 688.5K shares2025-Q3: 688.5K shares2025-Q4: 488.5K shares2026-Q1: 481.3K shares2026-Q2: 481.3K shares
$69.22(+380.04%)
2026-06-30
MAZE
MAZE THERAPEUTICS INC
3.27%5.03M$150.2M
+10.20%(+465.64K)
2025-Q2: 4.57M shares2025-Q3: 4.57M shares2025-Q4: 4.57M shares2026-Q1: 4.57M shares2026-Q2: 5.03M shares
$12.79(+112.57%)
2026-06-30
PHAT
PHATHOM PHARMACEUTICALS INC
2.95%12.47M$135.3M
+0.00%(+0)
2025-Q2: 12.47M shares2025-Q3: 12.47M shares2025-Q4: 12.47M shares2026-Q1: 12.47M shares2026-Q2: 12.47M shares
$12.77(-25.77%)
2026-06-30
PVLA
PALVELLA THERAPEUTICS INC NE
2.94%882.4K$134.8M
+0.00%(+0)
2025-Q2: 722.4K shares2025-Q3: 722.4K shares2025-Q4: 722.4K shares2026-Q1: 882.4K shares2026-Q2: 882.4K shares
$33.13(+371.30%)
2026-06-30

About Frazier Life Sciences Management L Pโ€™s portfolio

Frazier Life Sciences Management L P reports $4.59B in US-listed equity holdings across 41 positions in its most recent 13F filing. Its largest disclosed positions are MIRM (19.6%), NAMS (13.3%) and ERAS (10.0%). The top 20 holdings account for 88.81% of reported assets. Its disclosed equity book has returned +173.56% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
MIRM โ€” 19.9% ($899.06M)NAMS โ€” 13.6% ($613.03M)ERAS โ€” 10.1% ($457.55M)MBX โ€” 8.1% ($367.19M)ARQT โ€” 5.7% ($258.91M)TRVI โ€” 4.1% ($185.37M)KRYS โ€” 4.0% ($178.89M)MAZE โ€” 3.3% ($150.18M)PHAT โ€” 3.0% ($135.26M)PVLA โ€” 3.0% ($134.85M)Other โ€” 25.1% ($1.13B)
75%in top 10
  • MIRM19.9%
  • NAMS13.6%
  • ERAS10.1%
  • MBX8.1%
  • ARQT5.7%
  • TRVI4.1%
  • KRYS4.0%
  • MAZE3.3%
  • PHAT3.0%
  • PVLA3.0%
  • Other25.1%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
4
ACHVACHIEVE LIFE SCIENCE INC1.1%
DSGNDESIGN THERAPEUTICS INC0.6%
STTKSHATTUCK LABS INC0.6%
RLAYRELAY THERAPEUTICS INC0.4%
Added to
8
NAMSNEWAMSTERDAM PHARMA COMPANY+6.8%
ALLOALLOGENE THERAPEUTICS INC+491.2%
ASNDASCENDIS PHARMA A/S+68.9%
AURAAURA BIOSCIENCES INC+39.2%
+4 more
Trimmed
2
BBIOBRIDGEBIO PHARMA INC-55.1%
TRVITREVI THERAPEUTICS INC-0.0%

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Source filings

Holdings on this page are parsed from Frazier Life Sciences Management L Pโ€™s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1892134). View Frazier Life Sciences Management L Pโ€™s 13F filings on SEC

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