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Palo Alto Investors LP

Portfolio Manager
Palo Alto Investors LP
Performance
-4.35% (2026 Q1)
AUM (13F)
$653.86M
# of Holdings
51
Performance Rank
Allocation (Top 20)
85.67%

Palo Alto Investors LP Holdings Map

Top 50 Palo Alto Investors LP Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
INSM
INSMED INC
10.39%415.3K$67.9M
-15.16%(-74.21K)
2025-Q1: 987.2K shares2025-Q2: 865.1K shares2025-Q3: 491.8K shares2025-Q4: 489.5K shares2026-Q1: 415.3K shares
$18.99(+487.56%)
2026-03-31
ACAD
ACADIA PHARMACEUTICALS INC
9.78%2.87M$63.9M
+15.65%(+388.66K)
2025-Q1: 2.66M shares2025-Q2: 2.56M shares2025-Q3: 2.47M shares2025-Q4: 2.48M shares2026-Q1: 2.87M shares
$26.72(-2.82%)
2026-03-31
PTCT
PTC THERAPEUTICS INC
9.6%921.6K$62.8M
+1.96%(+17.69K)
2025-Q1: 404.2K shares2025-Q2: 406.5K shares2025-Q3: 862.6K shares2025-Q4: 903.9K shares2026-Q1: 921.6K shares
$47.94(+73.78%)
2026-03-31
BMRN
BIOMARIN PHARMACEUTICAL INC
5.92%685.2K$38.7M
-8.18%(-61.07K)
2025-Q1: 991.2K shares2025-Q2: 840.5K shares2025-Q3: 754.0K shares2025-Q4: 746.3K shares2026-Q1: 685.2K shares
$78.54(-24.90%)
2026-03-31
UTHR
UNITED THERAPEUTICS CORP
5.7%62.8K$37.2M
+7.95%(+4.62K)
2025-Q1: 105.2K shares2025-Q2: 95.5K shares2025-Q3: 58.2K shares2025-Q4: 58.2K shares2026-Q1: 62.8K shares
$116.67(+376.48%)
2026-03-31
ANAB
ANAPTYSBIO INC
5.41%638.2K$35.4M
-7.52%(-51.87K)
2025-Q1: 1.02M shares2025-Q2: 812.8K shares2025-Q3: 673.5K shares2025-Q4: 690.0K shares2026-Q1: 638.2K shares
$13.94(+354.82%)
2026-03-31
MIRM
MIRUM PHARMACEUTICALS INC
4.59%325.2K$30.0M
+107.88%(+168.75K)
2025-Q1: 64.7K shares2025-Q2: 64.7K shares2025-Q3: 64.7K shares2025-Q4: 156.4K shares2026-Q1: 325.2K shares
$69.52(+80.67%)
2026-03-31
DYN
DYNE THERAPEUTICS INC
4.58%1.65M$30.0M
+12.28%(+180.78K)
2025-Q1: 333.4K shares2025-Q2: 265.0K shares2025-Q3: 1.26M shares2025-Q4: 1.47M shares2026-Q1: 1.65M shares
$13.52(+70.64%)
2026-03-31
BIIB
BIOGEN INC
3.95%140.7K$25.8M
-23.34%(-42.85K)
2025-Q1: 204.9K shares2025-Q2: 205.8K shares2025-Q3: 185.7K shares2025-Q4: 183.6K shares2026-Q1: 140.7K shares
$256.88(-15.87%)
2026-03-31
IRON
DISC MEDICINE INC
3.93%401.7K$25.7M
+26.54%(+84.26K)
2025-Q1: 0 shares2025-Q2: 145.7K shares2025-Q3: 224.3K shares2025-Q4: 317.5K shares2026-Q1: 401.7K shares
$62.65(+21.73%)
2026-03-31

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