StockDriftsStockDriftsTop 50 Sio Capital Management LLC Holdings
| Stock | Company | % Port. | Shares | Value | Activity | Ownership | Avg. Cost | Date |
|---|---|---|---|---|---|---|---|---|
| AVR | ANTERIS TECHNOLOGIES GLOBAL | 9.36% | 5.55M | $54.6M | +3.03%(+163.02K) | $5.42(+73.29%) | 2026-06-30 | |
| COR | CENCORA INC | 8.42% | 173.6K | $49.1M | +72.05%(+72.69K) | $313.52(+0.10%) | 2026-06-30 | |
| MMS | MAXIMUS INC | 6.59% | 715.3K | $38.5M | -6.97%(-53.56K) | $79.20(-29.22%) | 2026-06-30 | |
| ALLO | ALLOGENE THERAPEUTICS INC | 4.75% | 13.32M | $27.7M | new | $2.15(-4.65%) | 2026-06-30 | |
| GMED | GLOBUS MED INC | 4.09% | 301.8K | $23.8M | new | $62.45(+37.56%) | 2026-06-30 | |
| GSK | GSK PLC | 3.92% | 436.7K | $22.9M | +13.17%(+50.82K) | $43.42(+14.05%) | 2026-06-30 | |
| TYRA | TYRA BIOSCIENCES INC | 3.81% | 695.3K | $22.2M | +14.84%(+89.88K) | $16.80(+50.53%) | 2026-06-30 | |
| WAY | WAYSTAR HLDG CORP | 3.26% | 925.8K | $19.0M | -43.62%(-716.40K) | $31.01(-20.09%) | 2026-06-30 | |
| IDYA | IDEAYA BIOSCIENCES INC | 3.07% | 480.4K | $17.9M | new | $33.52(+8.30%) | 2026-06-30 | |
| ORKA | ORUKA THERAPEUTICS INC | 2.89% | 177.1K | $16.9M | +33.68%(+44.62K) | $37.46(+200.28%) | 2026-06-30 |
| Performance Metric | 3-Year Annualized | 3-Year Cumulative | 5-Year Annualized | 5-Year Cumulative |
|---|---|---|---|---|
| Top 20 Holdings Weighted | +12.31% | +41.68% | +6.90% | +39.57% |
| Top 20 Holdings Unweighted | +12.27% | +41.50% | +6.19% | +35.02% |
Sio Capital Management LLC reports $604.29M in US-listed equity holdings across 57 positions in its most recent 13F filing. Its largest disclosed positions are AVR (9.4%), COR (8.4%) and MMS (6.6%). The top 20 holdings account for 73.3% of reported assets. Its disclosed equity book has returned +41.68% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.
Portfolio changes
Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.
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Holdings on this page are parsed from Sio Capital Management LLC’s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1482416). View Sio Capital Management LLC’s 13F filings on SEC