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TCG Crossover Management 13F Portfolio

Portfolio Manager
Tcg Crossover Management LLC
Performance
+21.76% (2026 Q2)
AUM (13F)
$4.16B
# of Holdings
54
Performance Rank
Allocation (Top 20)
79.53%
Latest filing
Q2 2026

Tcg Crossover Management LLC Holdings Map

Top 50 Tcg Crossover Management LLC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
ABVX
ABIVAX SA AMERICAN DEPOSITARY SHARES
19.24%6.01M$800.6M
-7.30%(-473.25K)
2025-Q2: 6.06M shares2025-Q3: 7.11M shares2025-Q4: 7.11M shares2026-Q1: 6.48M shares2026-Q2: 6.01M shares
$18.11(+570.42%)
2026-06-30
TNGX
TANGO THERAPEUTICS INC
6.82%9.08M$283.9M
-13.77%(-1.45M)
2025-Q2: 10.74M shares2025-Q3: 8.54M shares2025-Q4: 12.76M shares2026-Q1: 10.53M shares2026-Q2: 9.08M shares
$6.47(+295.36%)
2026-06-30
CGON
CG ONCOLOGY INC
6.27%3.67M$260.8M
+0.00%(+0)
2025-Q2: 3.67M shares2025-Q3: 3.67M shares2025-Q4: 3.67M shares2026-Q1: 3.67M shares2026-Q2: 3.67M shares
$43.73(+72.87%)
2026-06-30
COGT
COGENT BIOSCIENCES INC
4.52%4.85M$187.9M
-1.87%(-92.46K)
2025-Q2: 6.96M shares2025-Q3: 6.80M shares2025-Q4: 5.87M shares2026-Q1: 4.95M shares2026-Q2: 4.85M shares
$9.04(+319.53%)
2026-06-30
IMVT
IMMUNOVANT INC
4.13%4.46M$171.8M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 1.66M shares2026-Q1: 4.46M shares2026-Q2: 4.46M shares
$23.51(+77.92%)
2026-06-30
SYRE
SPYRE THERAPEUTICS INC
4.06%1.90M$168.7M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 1.10M shares2025-Q4: 1.90M shares2026-Q1: 1.90M shares2026-Q2: 1.90M shares
$19.61(+428.48%)
2026-06-30
DNTH
DIANTHUS THERAPEUTICS INC
3.93%1.68M$163.4M
+0.00%(+0)
2025-Q2: 1.50M shares2025-Q3: 1.68M shares2025-Q4: 1.68M shares2026-Q1: 1.68M shares2026-Q2: 1.68M shares
$25.05(+362.93%)
2026-06-30
MIRM
MIRUM PHARMACEUTICALS INC
2.99%1.06M$124.3M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 62.0K shares2026-Q1: 1.06M shares2026-Q2: 1.06M shares
$85.13(+18.22%)
2026-06-30
ZLAB
ZAI LAB LTD-ADR
2.8%6.14M$116.6Mnew2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 0 shares2026-Q2: 6.14M shares
$18.43(+40.57%)
2026-06-30
AMLX
AMYLYX PHARMACEUTICALS INC
2.7%6.24M$112.1M
+0.00%(+0)
2025-Q2: 5.94M shares2025-Q3: 6.24M shares2025-Q4: 6.24M shares2026-Q1: 6.24M shares2026-Q2: 6.24M shares
$3.15(+585.81%)
2026-06-30

About Tcg Crossover Management LLCโ€™s portfolio

Tcg Crossover Management LLC reports $4.16B in US-listed equity holdings across 54 positions in its most recent 13F filing. Its largest disclosed positions are ABVX (19.2%), TNGX (6.8%) and CGON (6.3%). The top 20 holdings account for 79.53% of reported assets. Its disclosed equity book has returned +218.91% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
ABVX โ€” 19.6% ($800.60M)TNGX โ€” 6.9% ($283.88M)CGON โ€” 6.4% ($260.77M)COGT โ€” 4.6% ($187.87M)IMVT โ€” 4.2% ($171.77M)SYRE โ€” 4.1% ($168.73M)DNTH โ€” 4.0% ($163.44M)MIRM โ€” 3.0% ($124.33M)ZLAB โ€” 2.8% ($116.61M)AMLX โ€” 2.7% ($112.14M)Other โ€” 41.6% ($1.70B)
58%in top 10
  • ABVX19.6%
  • TNGX6.9%
  • CGON6.4%
  • COGT4.6%
  • IMVT4.2%
  • SYRE4.1%
  • DNTH4.0%
  • MIRM3.0%
  • ZLAB2.8%
  • AMLX2.7%
  • Other41.6%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
8
ZLABZAI LAB LTD-ADR2.8%
AURAAURA BIOSCIENCES INC1.6%
EDITEDITAS MEDICINE INC0.9%
PHVSPHARVARIS BV0.8%
+4 opened
Added to
2
AVTXAVALO THERAPEUTICS INC+308.6%
MNPRMONOPAR THERAPEUTICS INC+53.9%
Trimmed
9
ABVXABIVAX SA AMERICAN DEPOSITARY SHARES-7.3%
TNGXTANGO THERAPEUTICS INC-13.8%
RVMDREVOLUTION MEDICINES INC-40.9%
BHVNBIOHAVEN LTD-61.6%
+5 more

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Source filings

Holdings on this page are parsed from Tcg Crossover Management LLCโ€™s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1839948). View Tcg Crossover Management LLCโ€™s 13F filings on SEC

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