Top 50 Dafna Capital Management LLC Holdings
| Stock | Company | % Port. | Shares | Value | Activity | Ownership | Avg. Cost | Date |
|---|---|---|---|---|---|---|---|---|
| RVMD | REVOLUTION MEDICINES INC | 20.09% | 562.6K | $105.4M | -3.11%(-18.05K) | $32.03(+570.11%) | 2026-06-30 | |
| XBI | SPDR S&P BIOTECH ETF | 5.93% | 196.5K | $31.1M | -38.30%(-122.00K) | $90.34(+74.90%) | 2026-06-30 | |
| CMPS | COMPASS PATHWAYS PLC | 5.43% | 2.01M | $28.5M | -16.82%(-406.93K) | $5.88(+128.60%) | 2026-06-30 | |
| STXS | STEREOTAXIS INC | 4.49% | 13.68M | $23.5M | +0.00%(+0) | $1.03(+33.86%) | 2026-06-30 | |
| NKTR | NEKTAR THERAPEUTICS | 4.24% | 318.4K | $22.2M | +92.75%(+153.20K) | $58.21(+26.87%) | 2026-06-30 | |
| DNLI | DENALI THERAPEUTICS INC | 3.62% | 739.0K | $19.0M | +132.03%(+420.51K) | $19.34(+26.16%) | 2026-06-30 | |
| IDYA | IDEAYA BIOSCIENCES INC | 3.53% | 497.2K | $18.5M | +4.30%(+20.50K) | $19.95(+81.97%) | 2026-06-30 | |
| ATRC | ATRICURE INC | 3.19% | 597.4K | $16.7M | +0.00%(+0) | $27.99(+59.96%) | 2026-06-30 | |
| XENE | XENON PHARMACEUTICALS INC | 2.89% | 250.8K | $15.1M | +0.00%(+0) | $14.00(+345.47%) | 2026-06-30 | |
| CYTK | CYTOKINETICS INC | 2.79% | 172.0K | $14.7M | -20.92%(-45.50K) | $33.77(+119.94%) | 2026-06-30 |
| Performance Metric | 3-Year Annualized | 3-Year Cumulative | 5-Year Annualized | 5-Year Cumulative |
|---|---|---|---|---|
| Top 20 Holdings Weighted | +30.49% | +122.22% | -0.28% | -1.38% |
| Top 20 Holdings Unweighted | +26.92% | +104.46% | +6.80% | +38.97% |
Dafna Capital Management LLC reports $524.36M in US-listed equity holdings across 88 positions in its most recent 13F filing. Its largest disclosed positions are RVMD (20.1%), XBI (5.9%) and CMPS (5.4%). The top 20 holdings account for 72.95% of reported assets. Its disclosed equity book has returned +122.22% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.
Portfolio changes
Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.
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Holdings on this page are parsed from Dafna Capital Management LLCโs Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1389933). View Dafna Capital Management LLCโs 13F filings on SEC