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Darwin Global Management 13F Portfolio

Portfolio Manager
Darwin Global Management LTD
Performance
-15.99% (2026 Q2)
AUM (13F)
$3.76B
# of Holdings
5
Performance Rank
Allocation (Top 20)
99.99%
Latest filing
Q2 2026

Darwin Global Management LTD Holdings Map

Top 5 Darwin Global Management LTD Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
RVMD
REVOLUTION MEDICINES INC
54.45%10.63M$2.05B
+380.77%(+8.42M)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 2.21M shares2026-Q2: 10.63M shares
$129.27(+57.58%)
2026-06-30
INSM
INSMED INC
17.91%6.43M$673.6M
-61.73%(-10.37M)
2025-Q2: 19.34M shares2025-Q3: 20.46M shares2025-Q4: 20.93M shares2026-Q1: 16.81M shares2026-Q2: 6.43M shares
$75.00(+64.99%)
2026-06-30
BLTE
BELITE BIO INC
12.14%3.08M$456.6M
+0.65%(+19.81K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 3.03M shares2026-Q1: 3.06M shares2026-Q2: 3.08M shares
$117.62(+38.42%)
2026-06-30
ABVX
ABIVAX SA
9.26%3.62M$348.2M
+4.41%(+152.93K)
2025-Q2: 0 shares2025-Q3: 3.16M shares2025-Q4: 3.18M shares2026-Q1: 3.47M shares2026-Q2: 3.62M shares
$55.68(+113.65%)
2026-06-30
ROIV
ROIVANT SCIENCES LTD
6.23%6.75M$234.3M
-0.74%(-50.00K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 6.80M shares2026-Q2: 6.75M shares
$24.70(+46.56%)
2026-06-30

About Darwin Global Management LTD’s portfolio

Darwin Global Management LTD reports $3.76B in US-listed equity holdings across 5 positions in its most recent 13F filing. Its largest disclosed positions are RVMD (54.5%), INSM (17.9%) and BLTE (12.1%). The top 20 holdings account for 99.99% of reported assets. Its disclosed equity book has returned +1.29% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
RVMD — 54.5% ($2.05B)INSM — 17.9% ($673.60M)BLTE — 12.1% ($456.59M)ABVX — 9.3% ($348.22M)ROIV — 6.2% ($234.33M)
100%in top 5
  • RVMD54.5%
  • INSM17.9%
  • BLTE12.1%
  • ABVX9.3%
  • ROIV6.2%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

Added to
3
RVMDREVOLUTION MEDICINES INC+380.8%
ABVXABIVAX SA+4.4%
BLTEBELITE BIO INC+0.6%
Trimmed
2
INSMINSMED INC-61.7%
ROIVROIVANT SCIENCES LTD-0.7%

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Source filings

Holdings on this page are parsed from Darwin Global Management LTD’s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1839209). View Darwin Global Management LTD’s 13F filings on SEC

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