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Great Point Partners 13F Portfolio ยท Jeffrey Jay

Portfolio Manager
Jeffrey Jay
Performance
+22.07% (2026 Q2)
AUM (13F)
$529.12M
# of Holdings
37
Performance Rank
Allocation (Top 20)
81.73%
Latest filing
Q2 2026

Great Point Partners LLC Holdings Map

Top 34 Great Point Partners LLC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
VOR
VOR BIOPHARMA INC
7.37%1.70M$31.3M
-2.86%(-50.00K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 1.37M shares2026-Q1: 1.75M shares2026-Q2: 1.70M shares
$27.55(-16.40%)
2026-06-30
ABVX
ABIVAX SA
6.41%204.3K$27.2Mnew2025-Q2: 1.29M shares2025-Q3: 150.0K shares2025-Q4: 0 shares2026-Q1: 0 shares2026-Q2: 204.3K shares
$39.56(+206.93%)
2026-06-30
VERA
VERA THERAPEUTICS INC
6.07%600.8K$25.8M
+201.40%(+401.49K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 199.3K shares2026-Q2: 600.8K shares
$42.14(-24.94%)
2026-06-30
ZURA
ZURA BIO LTD
5.86%4.22M$24.9M
+0.00%(+0)
2025-Q2: 3.17M shares2025-Q3: 3.82M shares2025-Q4: 3.82M shares2026-Q1: 4.22M shares2026-Q2: 4.22M shares
$7.23(-23.00%)
2026-06-30
ALMS
ALUMIS INC
5.68%856.1K$24.1M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 856.1K shares2026-Q2: 856.1K shares
$15.90(+59.23%)
2026-06-30
SLGL
SOL-GEL TECHNOLOGIES LTD
4.79%274.4K$20.3M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 274.4K shares2026-Q2: 274.4K shares
$60.68(+37.62%)
2026-06-30
DFTX
DEFINIUM THERAPEUTICS INC
4.71%425.0K$20.0Mnew2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 0 shares2026-Q2: 425.0K shares
$32.27(+32.10%)
2026-06-30
ANNX
ANNEXON INC
4.71%3.50M$20.0M
+40.00%(+1.00M)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 2.50M shares2026-Q2: 3.50M shares
$5.30(-0.11%)
2026-06-30
ORKA
ORUKA THERAPEUTICS INC
4.11%183.3K$17.4M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 183.3K shares2025-Q4: 183.3K shares2026-Q1: 183.3K shares2026-Q2: 183.3K shares
$35.23(+219.26%)
2026-06-30
MLTX
MOONLAKE IMMUNOTHERAPEUTICS
3.93%855.8K$16.7M
+71.16%(+355.81K)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 500.0K shares2026-Q2: 855.8K shares
$16.86(-1.97%)
2026-06-30

About Great Point Partners LLCโ€™s portfolio

Great Point Partners LLC reports $529.12M in US-listed equity holdings across 37 positions in its most recent 13F filing. Its largest disclosed positions are VOR (7.4%), ABVX (6.4%) and VERA (6.1%). The top 20 holdings account for 81.73% of reported assets. Its disclosed equity book has returned +104.65% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
VOR โ€” 7.6% ($31.30M)ABVX โ€” 6.6% ($27.23M)VERA โ€” 6.3% ($25.78M)ZURA โ€” 6.1% ($24.87M)ALMS โ€” 5.9% ($24.09M)SLGL โ€” 5.0% ($20.34M)DFTX โ€” 4.9% ($19.99M)ANNX โ€” 4.9% ($19.98M)ORKA โ€” 4.3% ($17.45M)MLTX โ€” 4.1% ($16.66M)Other โ€” 44.4% ($182.15M)
56%in top 10
  • VOR7.6%
  • ABVX6.6%
  • VERA6.3%
  • ZURA6.1%
  • ALMS5.9%
  • SLGL5.0%
  • DFTX4.9%
  • ANNX4.9%
  • ORKA4.3%
  • MLTX4.1%
  • Other44.4%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
8
ABVXABIVAX SA6.4%
DFTXDEFINIUM THERAPEUTICS INC4.7%
SGMTSAGIMET BIOSCIENCES INC3.7%
IFRXINFLARX NV1.6%
+4 opened
Added to
7
VERAVERA THERAPEUTICS INC+201.4%
IMMXIMMIX BIOPHARMA INC+265.0%
MLTXMOONLAKE IMMUNOTHERAPEUTICS+71.2%
IRDOPUS GENETICS INC+507.4%
+3 more
Trimmed
9
AMLXAMYLYX PHARMACEUTICALS INC-60.0%
NKTRNEKTAR THERAPEUTICS-44.7%
DRUGBRIGHT MINDS BIOSCIENCES INC-50.2%
SLNSILENCE THERAPEUTICS PLC-55.9%
+5 more

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Source filings

Holdings on this page are parsed from Great Point Partners LLCโ€™s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1281446). View Great Point Partners LLCโ€™s 13F filings on SEC

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