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Samsara Biocapital 13F Portfolio

Portfolio Manager
Samsara Biocapital LLC
Performance
+10.77% (2026 Q2)
AUM (13F)
$1.22B
# of Holdings
24
Performance Rank
Allocation (Top 20)
92.68%
Latest filing
Q2 2026

Samsara Biocapital LLC Holdings Map

Top 21 Samsara Biocapital LLC Holdings

Top 10 holdings

StockCompany% Port.SharesValueActivityOwnershipAvg. CostDate
SRRK
SCHOLAR ROCK HLDG CORP
31.16%6.90M$379.4M
+0.00%(+0)
2025-Q2: 5.61M shares2025-Q3: 5.61M shares2025-Q4: 6.90M shares2026-Q1: 6.90M shares2026-Q2: 6.90M shares
$16.44(+219.52%)
2026-06-30
ALMS
ALUMIS INC
14.67%6.35M$178.6M
+0.00%(+0)
2025-Q2: 4.80M shares2025-Q3: 4.80M shares2025-Q4: 5.76M shares2026-Q1: 6.35M shares2026-Q2: 6.35M shares
$9.73(+160.22%)
2026-06-30
MLYS
MINERALYS THERAPEUTICS INC
13.01%5.87M$158.4M
+0.00%(+0)
2025-Q2: 5.67M shares2025-Q3: 6.26M shares2025-Q4: 5.87M shares2026-Q1: 5.87M shares2026-Q2: 5.87M shares
$16.02(+60.05%)
2026-06-30
SEPN
SEPTERNA INC
8.66%3.15M$105.5M
+0.00%(+0)
2025-Q2: 3.15M shares2025-Q3: 3.15M shares2025-Q4: 3.15M shares2026-Q1: 3.15M shares2026-Q2: 3.15M shares
$21.87(+103.51%)
2026-06-30
NGNE
NEUROGENE INC
4.44%1.72M$54.0M
+0.00%(+0)
2025-Q2: 1.72M shares2025-Q3: 1.72M shares2025-Q4: 1.72M shares2026-Q1: 1.72M shares2026-Q2: 1.72M shares
$21.47(+68.34%)
2026-06-30
KLRS
KALARIS THERAPEUTICS INC
4.31%12.88M$52.4M
-0.52%(-66.91K)
2025-Q2: 11.45M shares2025-Q3: 11.45M shares2025-Q4: 12.95M shares2026-Q1: 12.95M shares2026-Q2: 12.88M shares
$8.64(-52.80%)
2026-06-30
SGP
SPYGLASS PHARMA INC
3.86%2.11M$47.0M
+0.00%(+0)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 0 shares2026-Q1: 2.11M shares2026-Q2: 2.11M shares
$25.91(+1.12%)
2026-06-30
STRO
SUTRO BIOPHARMA INC
2.9%1.06M$35.3M
+0.00%(+0)
2025-Q2: 219.7K shares2025-Q3: 219.7K shares2025-Q4: 204.5K shares2026-Q1: 1.06M shares2026-Q2: 1.06M shares
$29.92(-31.55%)
2026-06-30
IVA
INVENTIVA SA
1.96%6.31M$23.9M
+21.56%(+1.12M)
2025-Q2: 0 shares2025-Q3: 0 shares2025-Q4: 5.19M shares2026-Q1: 5.19M shares2026-Q2: 6.31M shares
$5.12(-10.07%)
2026-06-30
JBIO
JADE BIOSCIENCES INC
1.34%736.2K$16.4M
-24.01%(-232.56K)
2025-Q2: 531.2K shares2025-Q3: 531.2K shares2025-Q4: 968.8K shares2026-Q1: 968.8K shares2026-Q2: 736.2K shares
$32.45(-23.85%)
2026-06-30

About Samsara Biocapital LLCโ€™s portfolio

Samsara Biocapital LLC reports $1.22B in US-listed equity holdings across 24 positions in its most recent 13F filing. Its largest disclosed positions are SRRK (31.2%), ALMS (14.7%) and MLYS (13.0%). The top 20 holdings account for 92.68% of reported assets. Its disclosed equity book has returned +69.07% on a three-year cumulative basis. Figures reflect the Q2 2026 filing.

Portfolio concentration

Portfolio concentration
SRRK โ€” 33.6% ($379.37M)ALMS โ€” 15.8% ($178.55M)MLYS โ€” 14.0% ($158.40M)SEPN โ€” 9.3% ($105.46M)NGNE โ€” 4.8% ($54.00M)KLRS โ€” 4.6% ($52.43M)SGP โ€” 4.2% ($46.97M)STRO โ€” 3.1% ($35.29M)IVA โ€” 2.1% ($23.87M)JBIO โ€” 1.4% ($16.36M)Other โ€” 7.0% ($78.80M)
93%in top 10
  • SRRK33.6%
  • ALMS15.8%
  • MLYS14.0%
  • SEPN9.3%
  • NGNE4.8%
  • KLRS4.6%
  • SGP4.2%
  • STRO3.1%
  • IVA2.1%
  • JBIO1.4%
  • Other7.0%

Portfolio changes

What the fund actually did

Every reported change this quarter, grouped by direction. The signal is in the rotation, not any single trade.

New buys
1
ARTVARTIVA BIOTHERAPEUTICS INC0.8%
Added to
2
IVAINVENTIVA SA+21.6%
RANIRANI THERAPEUTICS HLDGS INC+22.0%
Trimmed
5
JBIOJADE BIOSCIENCES INC-24.0%
UPBUPSTREAM BIO INC-51.9%
XFORX4 PHARMACEUTICALS INC-23.8%
KLRSKALARIS THERAPEUTICS INC-0.5%
+1 more

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Source filings

Holdings on this page are parsed from Samsara Biocapital LLCโ€™s Form 13F filings with the U.S. Securities and Exchange Commission (CIK 1744967). View Samsara Biocapital LLCโ€™s 13F filings on SEC

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