StockDriftsStockDriftsTop 50 Siren, L.L.C. Holdings
| Stock | Company | % Port. | Shares | Value | Activity | Ownership | Avg. Cost | Date |
|---|---|---|---|---|---|---|---|---|
| SRRK | Scholar Rock Holding Corp | 14.75% | 10.83M | $532.2M | +0.00%(+0) | $12.90(+325.59%) | 2026-03-31 | |
| KYMR | Kymera Therapeutics Inc | 7.36% | 3.19M | $265.4M | -3.04%(-100.00K) | $38.10(+197.89%) | 2026-03-31 | |
| ERAS | Erasca Inc | 5.04% | 11.24M | $181.9M | +28.40%(+2.49M) | $4.18(+341.57%) | 2026-03-31 | |
| EWTX | Edgewise Therapeutics Inc | 3.87% | 4.43M | $139.6M | -2.20%(-99.73K) | $20.24(+95.44%) | 2026-03-31 | |
| ONC | BeOne Medicines AG | 3.83% | 465.0K | $138.1M | -7.00%(-35.00K) | $189.89(+56.75%) | 2026-03-31 | |
| TNGX | Tango Therapeutics Inc | 3.28% | 5.66M | $118.3M | -30.72%(-2.51M) | $7.38(+299.35%) | 2026-03-31 | |
| BCAX | Bicara Therapeutics Inc | 3.2% | 5.80M | $115.4M | +11.23%(+586.00K) | $19.87(+45.97%) | 2026-03-31 | |
| RVMD | Revolution Medicines Inc | 3% | 1.11M | $108.0M | -16.79%(-224.09K) | $45.25(+318.21%) | 2026-03-31 | |
| ARWR | Arrowhead Pharmaceuticals Inc | 2.81% | 1.62M | $101.3M | +7.66%(+115.00K) | $25.15(+233.95%) | 2026-03-31 | |
| MANE | Veradermics Inc | 2.64% | 1.51M | $95.1M | new | $63.15(+105.45%) | 2026-03-31 |
| Performance Metric | 3-Year Annualized | 3-Year Cumulative |
|---|---|---|
| Top 20 Holdings Weighted | +39.33% | +170.48% |
| Top 20 Holdings Unweighted | +30.03% | +119.83% |
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